Distribution of Crimean-Congo Hemorrhagic Fever Virus (CCHF) Infections Among Animals and Human in Diyala Province

In this study, 30 blood samples were collected from Human patients infected with CCHF virus residing in Alrazi Hospital, 30 samples from cattles and 30 from goats from the veterinary medical clinic in Baquba city. Also, 15 blood samples were taken from healthy individuals, 15 samples from healthy cattles and 15 samples from healthy goats as control groups. The study was carried out during the period from, 15th January to 30th June 2023 in Diyala Province. According to the results, the (Mean±S.E) of Human anti IgM antibodies was 2.40±0.26 in patients with CCHF and 2.13±0.23 in cattles with non-significant differences, while the (Mean±S.E) of anti IgM antibodies was 1.72±0.15 in goats with a significant difference between goats and humans (p=0.03).  The (Mean±S.E) of Human anti IgG antibodies was 1.42±0.11 in patients with CCHF and 1.27±0.12 in cattles with non-significant differences.  Also, the mean ±S.E   of anti IgG was 1.24±0.11 in goats with non-significant differences between the animals and Humans. The mean ±S.E  of anti-IgM Human antibodies was 2.40±0.26 compared to the control group 0.08±0.05 with a highly significant difference p<0.001. The mean of anti-IgG human antibodies was 1.42±0.11 compared to the control group 0.13±0.06 with a highly significant difference p<0.001. The mean of anti-IgM cattle antibodies was 2.13±0.23 compared to the control group 0.08±0.04, with a highly significant difference p<0.001. The mean of anti-IgG antibodies was 1.27±0.12 compared to the control group 0.09±0.04 with a highly significant difference p<0.001. The mean of anti-IgM goat antibodies was 2.13±0.23 compared to the control group 0.08±0.04 with a highly significant difference p<0.001. finally, the mean of anti-IgG antibodies was 1.27±0.12 compared to the control group 0.09±0.04 with a highly significant difference p<0.001

Cytogenetic Estimation of Broccoli Extract on Dexamethasone Treated Mice

The current study was intended to evaluate the active compounds found in hydro-alcoholic extract of Brassica oleracea var. italica(broccoli), also to estimates the percentage of chromosomal aberrations (CAs) ,mitotic index (MI) and micronuclei (MN) formation in mouse bone marrow cells .The mice were divided into, negative group received (0.2 ml of  Distilled Water)intraperitoneally ,positive group I was given single dose of dexamethasone (0.4 mg/kg for 24 h) and positive group II (acute toxicity assay) administrated with (0.2 ml) of  high level dose (800 mg/kg) of extract for 5 days. Interaction groups treated with  different doses of extract (50,100,200,400 and 600 mg/kg) for 5 days in addition to a single ( 0.4 mg/kg) of dexamethasone per each dose of extract. High level dose (800mg/kg) of broccoli extract had show null genotoxicity for bone marrow cells of mouse. Dexamethasone showed significant effects (P< 0.05)  in reducing mitotic index and increased chromosomal aberrations and micronuclei  in mouse bone marrow cells (in vivo). Broccoli extract significantly increased MI and reduced (CA ,MN) (P< 0.05) especially at does (400 mg/kg). Keywords- mitotic index, Micronuclei formation ,Chromosomal aberrations , Dexamethasone, Brassica oleracea var. italica (broccoli), hydro-alcoholic extract

Folic acid restores endothelial function in ACTH-induced hypertension

AbstractHypertension is associated with increased oxidative stress and vascular endothelium dysfunction. The aim was to study the effect of folic acid (FA) on hypertension, blood nitric oxide (NO), homocysteine (HCY), malondialdehyde (MDA) and reduced glutathione (GSH); aortic tissue glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD); and vascular endothelial function in adrenocorticotrophic hormone (ACTH)-induced hypertension rats. Rats were treated with saline or FA alone (0.04g/L/day orally, control), or subcutaneous ACTH-induced hypertension (0.2mg/kg/day, ACTH) groups. Treated FA groups were started before (Folic–ACTH, prevention) and during (ACTH–Folic, reversal) ACTH administrations. Systolic blood pressure (SBP), thymus/body weight ratio, blood urea, creatinine, NO, HCY, MDA and GSH; aortic endothelium-dependent vasodilator (EDD) in response to acetylcholine (ACh), aortic tissue extract for CAT, GPx, and SOD activity; and histopathological changes of aorta and kidney were assessed. Saline or FA alone did not change SBP (P>0.05). FA, in prevention study, significantly decreased SBP, increased serum NO and GSH, enhanced relaxation response (EDD%) to 1×10−4M ACh; increased aortic tissue GPx, CAT and SOD activity, also revealed nearly normal endothelial cell layer and moderately positive cytoplasmic staining for CD34+ expression versus ACTH-treated rats (P<0.05). In contrast, FA, in reversal study, did not show significant changes in most of the measured parameters as ACTH-treated group (P>0.05). FA can be used as an adjuvant therapy for prevention and treatment of ACTH-induced hypertension. The protective role of FA in ACTH-induced hypertension could be attributed via decreasing HCY, MDA (oxidative stress); increasing NO, GSH, GPx, CAT, SOD activity (antioxidants); and restoring endothelial dysfunction

Agreement between Cloposcopy and Pap smear in diagnosis of cervical lesions

The research was conducted in the department of obstetrics and gynecology at          Al-Assad and Tishreen university hospitals in Lattakia in the period between         (1/6/2016) – (31/12/2016). The study included (100) patients, who submitted to Colposcopy and Papanicolaou smear and biopsy was taken if needed to evaluate the agreement between Cloposcopy and Pap smear  in diagnosis cervical lesions.By evaluating Colposcopy and Pap smear as diagnostic means, the rate of abnormal Colposcopy was 27% while the rate of abnormal pap smear was 5%. The sensitivity of Colposcopy 85.71% was higher than the sensitivity of  Pap smear 57.14%, and the specificity of Colposcopy 7.14% was lower than the specificity of Pap smear 92.85%.The statistical study has shown that:              1-We found a significant agreement between Pap smear and Histopathology (p=0.011<0.05). 2-We didn,t find a significant agreement between Colposcopy and Histopathology (p=0.599>0.05), but after using Reid Colposcopic Index(RCI) a significant agreement was found between RCI and Histopathology (p=0.028<0.05). 3-We found a significant agreement between RCI and Pap smear (p=0.000<<0.05).    We conclude that Pap smear and Colposcopy are good and necessary screening tests for cervical cancer and pre cancer diagnosis.                                             تقييم التوافق بين الموجودات التنظيرية لعنق الرحم مع لطاخة بابانيكولاو                                          في تشخيص آفات عنق الرحم   أجري البحث في قسم التوليد وأمراض النساء في مشفيي الأسد وتشرين الجامعيين باللاذقية في الفترة الواقعة بين (1/6/2016) – (31/12/2016). شمل البحث (100) مريضة, أجري لهن تنظير مكبر لعنق الرحم ولطاخة بابانيكولاو، كما تم أخذ خزع موجهة بالتنظير عند الحاجة. وذلك لتقييم التوافق بين الموجودات التنظيرية لعنق الرحم ولطاخة بابانيكولاو في تشخيص آفات عنق الرحم. وبتقييم التنظير المكبر لعنق الرحم ولطاخة بابانيكولاو كوسيلتين تشخيصيتين لآفات عنق الرحم تبين أن نسبة الحالات الشاذة بالتنظير المكبر27%، بينما نسبة الحالات الشاذة بالفحص الخلوي للطاخة بابانيكولاو5%. كما تبين أن حساسية التنظير المكبر 85.71% أعلى من حساسية اللطاخة 57.14%، ونوعية التنظير المكبر 7.14% أقل من نوعية اللطاخة 92.85%. وبالدراسة الإحصائية تبين ما يلي: 1-وجدت علاقة إحصائية بين لطاخة بابانيكولاو والفحص النسيجي (P=0.011<0.05). 2-لم يثبت وجود علاقة بين التنظير المكبر لعنق الرحم والفحص النسيجي(P=0.599>0.05)، لكن بعد استخدام مشعر ريد التنظيري RCI في قراءة الموجودات التنظيرية فقد وجدت علاقة إحصائية بينه وبين الفحص النسيجي (P=0.028<0.05). 3-وجدت علاقة إحصائية قوية بين مشعر ريد التنظيري (RCI) ولطاخة بابانيكولاو (P=0.000<<0.05). وهكذا نستنتج أن كل من لطاخة بابانيكولاو والتنظير المكبر لعنق الرحم وسيلتي مسح جيدتين وضروريتين يمكن الاعتماد عليهما في الاستقصاء الأولي عن الآفات السرطانية وما قبل السرطانية لعنق الرحم

INTERPRETATION TRAINED NEURAL NETWORKS BASED ON GENETIC ALGORITHMS

ABSTRAC

BUILDING PHYSIOLOGICAL MEASURE FOR KARATE COACHES AND RELATION TO THE LEVEL OF PERFORMANCE

تهدف هذه الدراسة لباء مقياس نفسي لمدربي الكاراتيه و التعرف على تأثيره على مستوى الانجاز من خلال بناء مقياس للانجاز ، العلاقة مابين حالتهم النفسية ومستوى انجازاتهم. قام الباحثان باستعمال مقياس نفسي مناسب لطبيعة الدراسة ، وتم تطبيق البحث على مجموعة من مدربي الكاراتيه المسجلين بالاتحاد المصري للعبة حيث بلغ عدد المدربين عينة الدراسة (98) مدرب . أظهرت نتائج الاختبار مايلي : - أمكن التعرف على الأبعاد الاساسية للمقياس النفسى لمدربى رياضة الكاراتيه وهى ( مهارات الاتصال ، أحترام الذات ، القدرة على قيادة الفريق ) . - وجود علاقة إرتباطية دالة عند مستوى 0.05 بين درجات أبعاد المقياس . - وجود علاقة إرتباطية دالة عند مستوى 0.05 بين درجات عبارات السمات النفسية للمدرب . - مستوى السمات النفسية ( مهارات الاتصال ، أحترام الذات ) لمدربى رياضة الكاراتيه الذين يتميزون بعدد سنوات خبرة أكثر من عشرون عاماً مرتفع مقارنة بمستوى تلك السمات لدى المدربين الذين يتميزون بسنوات خبرة أقل من عشرون عاماً. - وجود علاقة بين مستوى الانجاز ومحاور المقياس النفسى لمدربى الكاراتيه . وتوصي الدراسة بتطبيق هذا البحث على عينة أكبر من مدربي الكاراتيه ، وكذلك الاهتمام بتنمية السمات الشخصيى لدى مدربي الالعاب القتاليةObjective of the Research The research aims to build a psychological measure to the karate coaches and identify: R The relationship of psychological measure with achievement of the karate coach through: 1) Building psychological measure for the achievement level of karate coaches; 2) To identify the relationship between psychological situation of their coaches and their level of achievement 3) Research Procedures 4) Research Approach: Researchers used questionnaire approach due to its suitability to the nature of the study. 5) Research Sample: Researchers selected research sample randomly from karate coaches registered with Egyptian Union of (98) coach Conclusions: The conclusions made by the Researcher of results related to using Statistical Treatments, the following conclusions were derived: * Identifying the basic dimensions of psychological measure for karate coaches (skills of: communication, self-esteem and ability to lead the team, * Availability of associative relation at the level of (0.05) between the measure dimensions; * Availability of associative relation at the level of (0.05) between the psychological traits of the coach; * The level of psychological traits (communication skills and self-esteem) for karate coaches who are experienced of more than twenty years compared to the level of those traits for the coaches who have experience that less than twenty years; * Relationship between the achievement level and pivots of psychological measure of the karate coaches. Recommendations Due to the distinguish nature of this research, within the limitations of abstracts, the Researcher recommends the following: To apply the measure on the largest samples of same specialization and other samples of fighting sports in order to identify the psychological traits of those coaches; Pay attention to develop psychological traits of karate coaches, specially fighting sports in general

Surface Roughness Effect on Discharge Coefficient of Combined Cylindrical Weir Gate Structure

The aim of this research is to investigate the effect of surface roughness on the performance of weir and gate. An experimental study in a laboratory flume is carried out to study flow over and under cylindrical weir gate in combined structure as flow measurement device. Four models having different diameters were tested in a laboratory flume. In each model, the surface was roughed four times. The results of the test show logical negative effect of the increase of surface roughness on the performance. The performance of the combined structure improved with decrease ratio of roughness to the upstream head (Ks/H) and with the increase of the total head to the diameter of the weir (H/d). Empirical relations were obtained to estimate the variation of discharge coefficient (Cd) in terms of some dimensionless parameters. Within the limitations of the present experimental work an equation to predict the discharge is proposed with R2 of 0.936. Finely the contribution of the gate increases relative to the weir when the surface roughness increases